The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Zetia may also increase the amount of cholesterol thats stored in your gallbladder. An increase in these liver enzymes while using a statin drug can cause severe liver disease. Zetia can also be used with statin drugs in adults. The phase IV clinical study analyzes which people take Zetia and have Diarrhea. About Postural orthostatic tachycardia syndrome. The cause of the disorder is unknown. If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. It also helps keep the drug from harming the environment. Muscle-related problems are a possible side effect of Zetia when used with other medications. A decrease in the transport of intestinal cholesterol to the liver reduces stores of hepatic cholesterol. Zetia may also be used off-label for other conditions. To reduce your symptoms in . What foods should I avoid while taking Zetia. These can be signs of rhabdomyolysis (muscle breakdown), which is a serious medical condition. Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system, Leqvio side effects: What you should know, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, 2.4% of people who took a statin drug alone, 2.5% of people who took Zetia with a statin drug, 2.2% of people who took a statin drug alone, 3.2% of adults and children who took Zetia with a statin drug experienced muscle pain, 2.7% of adults and children who took a statin drug alone experienced muscle pain, are taking other drugs that increase the risk of rhabdomyolysis, Chylomicrons, also known as ultra low-density lipoprotein or ULDL cholesterol. Since every POTS patient is different, some may primarily experience gastrointestinal symptoms, such as nausea, vomiting or poor feeding, Berger explained. An increase in levels of liver enzymes doesnt usually cause any symptoms. Nexlizet (bempedoic acid/ezetimibe) is a prescription tablet used to lower LDL (bad) cholesterol in certain people. These tests will look at your cholesterol levels and also your liver enzyme levels. Zetia can cause muscle-related side effects. Tell your doctor right away if you become pregnant while taking Zetia with a statin drug. Physicians who treat dysautonomia can be located on our Physician List. Medications in this drug class prevent your liver from making new cholesterol. Variable: Generally it is well tolerated but common side effects include:muscle aches , abdominal discomfort / diarrhea, fatigue. You can take Zetia with or without food. Total cholesterol levels were reduced by an average of: LDL (bad) cholesterol levels were reduced by an average of: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. Your child can take Zetia with or without food. Other interactions can increase side effects or make them more severe. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. In the video she posted on Thursday, the "Real Housewives of New York City" alum detailed her suffering from a severe dehydration issue and shared that her doctor . If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. If youre interested in finding an alternative to Zetia, talk with your doctor. Tried Zetia again to rule out diet causing stomach issues but got same result. The brand name for this drug combination is Vytorin. (Mixed hyperlipidemia is also known as mixed high cholesterol.). However, skip your missed dose if its almost time for your next dose. POTS-related fatigue is physical in nature . If youve had an allergic reaction to Zetia or any of its ingredients, you should not take Zetia. Stopping Zetia treatment shouldnt cause any noticeable side effects. It can cause mild side effects and, less commonly, serious side effects. The symptoms develop immediately and include dizziness and an intense headache. Effects of coenzyme Q10 on statin-induced myopathy: An updated meta-analysis of randomized controlled trials. The following information describes dosages that are commonly used or recommended. joint pain *. If any of the following factors or conditions apply, you may have a higher risk of developing these muscle problems: If you have muscle-related side effects during Zetia treatment, talk with your doctor. Also, Zetia use may cause increased liver enzyme levels, especially if its taken with a statin drug. Cholesterol is made naturally in your liver. For mixed high cholesterol, Zetia is FDA-approved to decrease levels of: For this purpose, Zetia is used with a low-cholesterol diet and is taken with other drugs. (A class of medications is a group of drugs that work in a similar way.) Pots or postural tachycardia syndrome is, also known as postural orthostatic tachycardia syndrome, is a condition that affects the flow of blood in the heart and brain. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. These symptoms can be signs of an infection. This makes it difficult to keep an upright posture without abnormal heart-rate (tachycardia) and/or sympathetic activity. You should store Zetia tablets at a room temperature of 77F (25C) in a tightly sealed container away from light. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Using Zetia for high cholesterol. Talk with your doctor if youre concerned about your risk of memory loss while using Zetia alone or with a statin drug. diarrhea. You may also want to check out the online communities at Bezzy. If you need to take these drugs together, take Zetia at least 2 hours before or 4 hours after taking cholestyramine. No, hair loss isnt a known side effect of Zetia. Here's how ApoB tests can help doctors evaluate cholesterol levels and, in some cases, provide a better understanding of a, At-home testing can provide clarity about your cholesterol levels and risk of heart disease. Depending on your age or other medical conditions you may have, you may be at higher risk of developing rhabdomyolysis while taking Zetia. POTS was also linked, to a lesser degree, to Covid vaccination with an mRNA vaccine, according to the new study. Your doctor will likely start you on the typical dosage approved to treat your condition. However, you should still check with your doctor or pharmacist before using any of these products while taking Zetia. They often originate at the base of the skull and spreading on the back of the head and neck. It can be taken with or without fenofibrate in adults. Zetia may cause serious side effects including: muscle pain, muscle tenderness or weakness, fever, unusual tiredness, and. Statins are drugs used to lower cholesterol. This can cause gallstones (hardened stones in your gallbladder). The heartbeat increases with a feeling of the heart fluttering. (A class of drugs is a group of medications that work in a similar way.) Lying down on the bed, and raising your legs. . All rights reserved. Zetia is sometimes used with medications in the statin drug class. Recently, POTS has been diagnosed in some people who have had COVID-19. Medications in the fibrate drug class are used to treat high cholesterol. They can both be taken with or without food. Some people witness mild symptoms, some have a big impact on their lives due . If you have liver problems, your liver may not work properly to remove medications such as Zetia from your body. They may also check you for signs of muscle breakdown or kidney damage. This is especially helpful to do when you first start taking new drugs or using a combination of treatments. Zetia is metabolized in the small intestine and liver. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. In these groups, joint pain occurred in: The length of time that adults and children experienced joint pain while taking Zetia in these clinical studies isnt known. This may be caused by genetics, smoking, not getting enough physical activity, or eating too many foods that are high in cholesterol. joint or muscle pain*. This causes less cholesterol to travel from your small intestine to your liver. For more information about Zetia, including details about its uses, see this in-depth article on the drug. Talk with your doctor if you have questions about managing your blood pressure or blood sugar while using Zetia. stomach pain. Porphyrias have been associated with POTS symptoms (Stewart & Hensley, 1981). You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. If you need financial support to pay for Zetia, or if you need help understanding your insurance coverage, help is available. However, you may still experience muscle problems if you use Zetia alone. This lack of blood to the brain and other organs can cause a variety of symptoms, including: Fainting. Nausea/Vomiting. For most people, CoQ10 isnt a harmful or dangerous supplement. (Primary hyperlipidemia is also called primary high cholesterol.) Some people experience mild side effects with Zetia. Crossing your legs in front of each other while standing, rocking up and down on your toes. However, be sure to take the dosage your doctor prescribes for you. If youre using Zetia while sexually active with a female who could become pregnant, talk with your doctor about your birth control needs. Side effects of Lipitor and Zetia that are similar include diarrhea and joint pain. stuffy nose. Dont take an extra dose to make up for your missed dose. For more information, see the How Zetia works section below. Lipitor is available in a generic form called atorvastatin. Zetia can be used to treat high cholesterol or homozygous sitosterolemia (a condition that causes high fat levels) in certain people. But its possible that some side effects may continue to affect you for as long as youre taking the medication. Symptoms of liver damage include: If you have any of the above symptoms of liver damage, tell your doctor right away. Zetia contains the active drug ezetimibe. Talk with your doctor if you experience diarrhea while taking this medication. Watch Part 2 here: https://youtu.be/HPfo2QOa89YHello Friends! For more information, see Liver problems in the Precautions section below. Below are examples of these side effects. Crestor is available in a generic form called rosuvastatin. What are the serious side effects of Zetia? It can develop suddenly or gradually over time. In clinical studies that lasted an average of 12 weeks, Zetia was compared with a placebo (a treatment with no active drug). Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. If you have a history of heavy alcohol use and are taking Zetia with a statin drug, you may have a higher risk of side effects. Cholesterol absorption inhibitors prevent your small intestine from absorbing cholesterol. In clinical studies, Zetia has been found to be effective for treating mixed high cholesterol when used with fenofibrate. The autonomic nervous system is in charge of all bodily functions that we don't have to think about, such as: The sympathetic nervous system is part of the autonomic nervous system. Zetia is available as a tablet that you take by mouth. Zetia comes as a tablet that you swallow. Total cholesterol is the overall amount of cholesterol found in your blood. 4. These drugs havent been directly compared in clinical studies. Phase IV trials are used to detect adverse drug . Talk with your doctor about your health history before you take Zetia. Ways to reduce the symptoms. They may suggest foods that can help lower your cholesterol and reduce your risk of weight gain. The underlying cause is not known, although it sometimes follows bedrest after injury or illness. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Others may experience GI issues in conjunction with other symptoms, such as fainting. Less commonly, taking Zetia may lead to serious side effects. Ezetimibe can cause the breakdown of muscle tissue . Learn more about some of the side effects that Zetia may cause. You can take Zetia with or without food. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia that is estimated to impact between 1,000,000 and 3,000,000 Americans, and millions more around the world. Before taking Zetia, talk with your doctor and pharmacist. However, some people have reported experiencing memory loss when taking statin drugs. But if they become more severe or dont go away, talk with your doctor or pharmacist. However, side effects are generally mild and go away as the body adjusts to the medication. Would a lower dose of Zetia help to reduce my risk of side effects? For this purpose, Zetia may be used alone or with fenofibrate. Twelve weeks of treatment with Zetia and atorvastatin or simvastatin was compared with atorvastatin or simvastatin used alone. Lipitor is also FDA-approved for the following conditions when used with a low-cholesterol diet: primary dysbetalipoproteinemia in adults (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), liver complications, such as high levels of, Both Zetia and Crestor are FDA-approved to treat the following conditions* when used with a. Crestor is also FDA-approved for the following conditions in adults when used with a low-cholesterol diet: primary dysbetalipoproteinemia (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), pain on the right side of your body, below your ribs, in adults as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin drug), in adults in combination with a fenofibrate, in combination with statins, in people with hepatic disease, in combination with statins, in people with elevated hepatic transaminases, in combination with statins, during pregnancy or in someone planning to become pregnant, in combination with statins, while breastfeeding, in people who have a known allergy to Zetia. People who may be at higher risk of this side effect include those who: Tell your doctor if any of the above apply to you before starting Zetia treatment. Phase IV trials are used to detect adverse drug . If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. Youll likely take it once a day. This is not a complete list of side effects and others may occur. Zetia may not be right for you if you have certain medical conditions or other factors that affect your health. This is because large meals can cause blood to pool excessively in the abdomen. Here is a list of conditions that the Food and Drug Administration (FDA) has approved Zetia and Lipitor to treat. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. Zetia can cause mild or serious side effects. Instead, it belongs to a class of drugs called cholesterol absorption inhibitors. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. They can tell you about other medications that may work well for you. sinusitis. For more information, see the How Zetia works section below. Zetia is sometimes used with medications in the statin drug class. Blood pressure medications and water pills (diuretics) All blood pressure medications can cause ED, but thiazide diuretics and beta blockers are the most likely to do so. For those who aren't familiar with POTS, it is an often-disabling neurological condition that causes your heart rate to rise a great deal when you are upright, and often blood pressure drops when you are upright (when it should be rising), and it causes fainting, fatigue, headache, nausea, face and hand tingling, and blood pooling in legs. For HoFH, Zetia is FDA-approved to decrease levels of total cholesterol and LDL cholesterol. As Zetia from your body was compared with atorvastatin or simvastatin used alone or with fenofibrate the... Absorption inhibitors used off-label for other conditions of Lipitor and Zetia that are commonly used or recommended increased enzyme! 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You first start taking new drugs or using a statin drug class possible side effect of Zetia when used medications...
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