Fort Myers, FL - Isaac James Blood, 46, of Brewer, Maine, and Fort Myers, Florida, passed away unexpectedly in his sleep on December 26, 2022. Update 1.7.7 has arrived for The Binding of Isaac: Rebirth, and here's the full list of changes and fixes added with this patch. Characters Rooms purple, pink, mask, face, Puts a shield in front of Isaac which blocks projectiles, The shield will rotate based on the direction in which Isaac is firing tears, * angel room pool, god room pool, angel room item, blue, silver, metal, Gives Isaac a laser that will fire at random intervals in addition to your normal tears, Each laser does damage equal to your current tear damage, The laser will occasionally fire with one of these effects: Hook Worm, Spoon Bender, Tiny Planet, Mysterious Liquid, Rubber Cement, Luck has no effect on the rate at which Tech.5 fires and does not scale with items that increase your tears stat, UNLOCK: Unlock this item by beating Challenge #18 (The Host), * technology.5, tech 5, item room, treasure room, item room pool, white, red, eye, robot, Isaac now shoots two tears at once, but dealing -20% damage each, Unlike the Inner Eye and Mutant Spider items, this double shot item does not give a tears down, * 20 20, 2020, item room, treasure room, item room pool, black glasses, spectacles, Reveals the locations of the secret and super secret room for the current floor and all future floors, UNLOCK: Unlock this item by donating 10 pennies to the Shop, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, This allows you to choose between the item that originally spawned and a HP upgrade every time, This effect applies to most items, including those in the shop and devil room. Interestingly enough, the beam will look like a G clef symbol. When used, the D12 re-rolls any rocks into another random type of object (e.g. Endings. Time is the essence", "Sleeping gatekeepers will need to be awoken with a loud sound", UNLOCK: Unlock this card by beating Challenge #11 (Glass Cannon). as Bethany, Gives you a random syringe effect every room, The effect can be The Virus, Roid Rage, Speed Ball, Experimental Treatment, Synthoil, Euthanasia or Growth Hormones, Placed bombs explode after 0.66 seconds instead of the usual 1.5 seconds, This was called Exploded Firecracker in Antibirth, Farts produced by Isaac or familiars will be twice as large, Chance for enemies to burn when entering a room, The chance for this effect to activate is effected by your Luck stat, This includes key blocks and golden chests, Pickups left on current floor will appear in the starting room of the next floor, up to a maximum of 4 pickups, Active items will be rerolled upon using them, Using with Book of Virtues will only reroll the item the book is holding, Has no effect with Notched Axe due to how its durability works, UNLOCK: Unlock this trinket by defeating Mother as Eden, Random luck-based tear effects have an extra chance of occurring, The additional chance is effectively +3 Luck Up, Picking up red hearts now has a high chance to spawn 1-4 blue attack spiders, instead of giving you health back, This effect also works while fully healed, giving a guaranteed chance of getting spiders, While missing any red health the chance for spiders is less, Works for characters that don't use red health, which always gives you spiders, Hearts in Shops can be converted into spiders for free, Gives your familiars improved rate of fire while held, In Antibirth this trinket was called Song of the Siren, UNLOCK: Unlock this trinket by bombing the skull left by The Siren boss after her death, While held at the start of each floor, this trinket spawns four wisp familiar orbitals around Isaac, These wisps are the same as the ones created by the Book of Virtues item, UNLOCK: Unlock this trinket by beating the Boss Rush as Bethany, Your active item no longer gains charges, but battery drops become much more common, UNLOCK: Unlock this trinket by blowing up 10 Battery Beggars, Tears that miss enemies will redirect themselves and travel 90 degrees towards enemies, Tears must be roughly 2 tiles or closer to activate this effect, +10 Luck while held, but the trinket is destroyed when damage is taken, Blood donation machines, Curse Rooms and Sacrifice Rooms wont destroy it, Taking a hit and activating Holy Mantle won't destroy it, Can be dropped in order to avoid breaking it, This trinket is automatically given to you after clearing 3 bosses without taking damage, Treasure Rooms are replaced with Red Treasure Rooms, which contain a deal with the devil in place of a regular item pedestal, If an item room has not yet been entered, it can be transformed to either a regular or Red Treasure Room by picking up or dropping this trinket before entering, Does not affect the mirrored treasure room in Downpour II, UNLOCK: Unlock this trinket by defeating Mother as Azazel, Every time you pick up a coin, you have a small chance to gain 1 bar of charge on your active item, The chance for this effect to happen is 1/6th of the value of the coin picked up, Can only activate once per coin collected, In Antibirth this trinket was called Electric Penny, UNLOCK: Unlock this trinket by donating to a battery beggar until he pays out with an item 5 times, While held, your familiars will now orbit around Isaac instead of following behind him, Activates your active item just before damage would be taken, It doesn't activate for free - the charges are used up as normal if this effect activates. Additional copy of Monstro's Lung adds 3-5 more rings. This doesn't affect item pedestals found before picking up Birthright. Trinkets Seeds They can be used to damage enemies, Saturnus tears can't break objects such as poop and TNT barrels, Isaac now shoots ice tears that slow enemies. He behaves the same as how Esau works with Jacob, following your exact movements, Disappears after the current room or if he takes enough damage and dies, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Forgotten, Creates 6 wisps, similar to the Book of Virtues effect, Mosts wisps will be the standard blue ones, but have a chance to have random special properties, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Bethany, Spawns Esau as a temporary familiar, who copies your exact movements the same as how the Jacob & Esau character works, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Jacob, Once picked up, you gain unlimited key use for the rest of the floor, Using a 'Bombs are Key' pill with this effect will swap your Gold Key for a Gold Bomb, Once picked up, you gain unlimited bomb use for the rest of the floor, Using a 'Bombs are Key' pill with this effect will swap your Gold Bomb for a Gold Key, UNLOCK: Unlock this item by beating challenge #23 (Blue Bomber), Fully charges your active item when picked up, Also, you take a full heart of damage when picked up. Lazarus - Every time Lazarus dies, gives +21.6 temporary Damage Up, gradually fading over 1 minute. Azazel is a playable character in The Binding of Isaac: Four Souls. The beam will visually go downwards despite actually fired in the direction Isaac originally did. Binding of Isaac: Rebirth Item guide series===Support me===Monthly on Patreon: https://www.patreon.com/syncerOne-time donation: https://www.paypal.com/cgi-bi. Corpse II drops same as Womb II, UNLOCK: Unlock this item by beating the Dark Room with Lazarus, * red chest pool, red chest item pool, shop room pool, shop item pool, blue box, pandoras box, When used, turns Isaac invincible and gains +0.28 speed for a 5 seconds, You cannot fire tears while the stump is active, Very similar to the My Little Unicorn item but does not deal contact damage, When used with Mom's Knife, you can still deal contact damage but will be unable to change the way the knife faces while the effect is active, * item room, treasure room, item room pool, white, lump, grey, gray, blob, While in a hostile room your speed raises at a rate of +0.065 per game tick, When you hit a speed stat of 2.0, Isaac will gain an invincibility effect for 5 seconds, increasing speed and allowing him to run into enemies to deal 40 contact damage per hit, The time it takes for the effect to activate becomes shorter with a higher base Speed stat, * astrology, astronomy, item room, treasure room, item room pool, blue, glow, circle, horns, Gives huge horns which stick out, allowing you to deal 18 contact damage if you hit something with enough speed, Will not deal contact damage unless you are moving fast enough (at least 0.8 speed), REPENTANCE - Aries now prevents receiving contact damage if ramming and killing enemies at full speed, * astrology, astronomy, item room, treasure room, item room pool, black, blue, cyan, glow, After getting hit once, you gain a damage reduction for the rest of the room similar to The Wafer item (-50% damage taken), * astrology, astronomy, item room, treasure room, item room pool, cyan, black, the lost item pool, The bigger beam granted by double Brimstone synergizes with other items as expected. It also changes tears to a chargeable laser that pierces all objects in its path (including enemies, environmental hazards and walls). with a Brimstone Curse which makes them more vulnerable to Brimstone attacks and causes them to explode when killed by Brimstone; Tainted Eve's clots are no longer lost when recalled by Sumptorium if she has full health, instead they will drop to . Counts as 1 of 3 evil items needed towards the Leviathan transformation. Blood clots can be life-threatening depending on their location and severity. Sad Bombs: Bob's Brain will fire tears upon exploding. Brimstone's charge (open mouthed laser) will overlap any item that is on the player's face; this is obviously a graphical bug. REPENTANCE - Mitre now only has a 33% chance to convert red heart drops into soul hearts (down from 50%). Can only be accessed via the Red Key, Crystal Key or Cracked Key. See previous icon for normal character effects, Tainted Isaac - Adds 4 more spaces for passive items, Tainted Maggy - Adds 1 extra real heart container that doesn't deplete, Tainted Cain - Doubles picks dropped when touching an item, Tainted Judas - Increases the range in which Dark Arts hits enemies and tears, Tainted ??? All floors guaranteed to have an Arcade except the Chest & Dark Room floors, Judas - Gives a passive Book of Belial item similar to Book of Virtues. Cathedral: 1 Angel Room Item + 1 Eternal Heart, Pandora's Box considers XL floors to always be the first floor of a chapter, Alternative floors drop the same stuff e.g. Activating Sumptorium restores Tainted Eve's health (if possible) and axes living clots (though not all of them? Gives a small chance when entering a room for enemies to be petrified for 4 seconds. It will hunt down other enemies, dealing contact damage which scales with your tear damage, After 5 seconds the red soul explodes (Isaac doesn't take damage from this effect), UNLOCK: Unlock this item by defeating The Beast as The Lost, *, this item is irrelevant 99.94% of you wont kill the beast as the lost me included :(, When used, gives you number of blue flame orbitals based on the number shown over this item, It starts at 1, and increments each activation, giving you more familiars each time you use it, The flames fire tears at the same time Isaac does, that deal a flat 3 damage, If a flame touches an enemy, it deals contact damage equal to double your current tear damage and then disappears, You can have a maximum of 24 flame orbitals at once, Each flame has a chance to spawn as one of many variants, such as green flames that poison enemies, or a crucifix flame that spawns a random horseman familiar + Locusts when it is extinguished, UNLOCK: Unlock this item by defeating The Beast as Bethany, Soul hearts give you small permanent stat increases when picked up, Possible stats include +0.3 Range Up, +0.2 Luck Up, +0.2 Damage Up, +0.1 Tears Up, +0.04 Speed Up, UNLOCK: Unlock this item by defeating Greed Mode as Bethany, Spawns a random charmed enemy which fights by your side and copies your exact movements, similar to how Jacob & Esau work, The familiars fire tears at the same time as Isaac, and have a visible health bar showing how much damage they can take before dying, UNLOCK: Unlock this item by defeating The Beast as Jacob & Esau, You respawn as a tiny version of Isaac, with a greatly reduced hitbox and +0.2 Speed Up, When the effect activates you deal 35 damage to nearby enemies, Once unlocked, if you have already unlocked the tainted version of the character you're playing as, Inner Child is guaranteed to spawn in the hidden closet on the Home floor, UNLOCK: Unlock this item by defeating Greed Mode as Jacob & Esau, Item pedestals now cycle between 5 random items, UNLOCK: Unlock this item by defeating The Beast as Tainted Isaac, Enemies that touch Isaac will now bounce off him and fly off in the opposite direction, Bounced enemies will take 10 damage if they slam into the wall, This item also gives a random chance for enemy shots to bounce off you without taking damage, UNLOCK: Unlock this item by defeating The Beast as Tainted Magdalene, 33% chance to reroll items with a quality of 2, Quality is a hidden mechanic in Repetance for all items and ranges from 0-4. Chapters A familiar fly that moves in a straight line and attaches itself to the first obstacle or wall it comes into contact with in each room. white, square, When used, you have a chance of getting one of the three following effects: Treasure Map (floor layout), Compass (map icons) or Blue Map (secret room locations), REPENTANCE - Book of Secrets now avoids giving mapping effects that the player already has. * , the lost item pool, head, bone, grey, gray, Gives Isaac a higher chance to find pills, Gives Isaac a higher chance to find Tarot cards after clearing a room or from chests, After clearing a room, you have a chance to heal for half a red heart, *, the lost item pool, silver, metal, grey, gray, isaacs fork, When taking damage, Isaac has a chance to deal damage to the entire room in a Necronomicon style effect, The chance to damage enemies is affected by your luck stat and at +50 or more Luck it will activate 50% of the time, * , the lost item pool, pink, purple, paper, red, Everytime you pick up a penny, you have a 25% chance to spawn a red heart on the floor, UNLOCK: Unlock this item by beating the Chest with Samson, * , the lost item pool, red, coin, cent, money, Everytime you pick up a coin, you have a 25% chance to spawn a bomb on the floor, UNLOCK: Unlock this item by beating Challenge #13 (Beans! REPENTANCE - Dead Sea Scrolls now displays the name of the given effect, and can no longer give Kamikaze. Effects All your items and consumables are temporarily removed while in the abandoned mine, The room to access Knife Piece 2 only appears if you have Knife Piece 1 already, You can skip pressing the 3 yellow buttons if you have the ability to fly and have 2 bombs to force open the door, When combined with Knife Piece 1, can be used to stab the fleshy door in the Mausoleum II, which then leads to the Corpse floor and the Mother boss, This is a one time use item that teleports you to an alternate floor, which contains every single item in the game, The items are spread between several different rooms all on pedestals. Manage all your favorite fandoms in one place! Spawns another Vurp! in shops or devil rooms), The only way to survive the falling sword is either through extra lives, by using items that would make you invincible, such as Gnawed Leaf or playing as The Lost. Transcendence The Compass PHD Rosary XRay Vision Lucky Foot Magneto Treasure Map The Ladder Charm Of The Vampire The Battery Steam Sale Dead Cat Lord Of The Pit Spelunker Hat Mr. Mega The Wafer 9 Volt Bobby-Bomb Collection Grid - When used will consume your current trinket, destroying it and giving you its effect permanently. Endings. He was born May 5, 1976, in Bangor, Maine, to James and Sarah Blood. Unlocked by beating Isaac with Samson. Entity ID Endings. poop, pots), Counts as 1 of 3 cat items needed towards the Guppy transformation, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Cain, Item Pool: Devil Room, Curse Room, Red Chest, Spawns a Keeper familiar, that shoots triple tears and follows your exact movements as you walk, The keeper has 3 health coins and can die if it takes enough damage. Items picked up are not shared between the two characters, UNLOCK: Unlock this item by defeating The Beast as Tainted Jacob, When activated, Isaac's tears are replaced by a bone sword and he goes on a killing rampage, gaining +0.4 Speed, +3 Flat Damage Up for 5 seconds, The sword deals x3 damage if used at close range, or x1.5 damage if charged up and thrown, Clearing rooms doesn't charge this item - charge is added equal to damage taken by enemies. No longer reduces your devil/angel room chances when used, * item room, treasure room, item room pool, the lost item pool, bomb, tnt, clock, red, When used, causes all enemies in the current room to run away from Isaac in fear for 5 seconds. This means the trinket does nothing if your active item isn't fully charged, Single-use active items are consumed as normal, Doors can be opened without using up a key, However, when entering the door you are taken to a blue womb room with enemies to defeat. It will attempt to hide behind you when shooting. Seeds For Items it increases by 2 coins * the number of purchases. Bosses Tear Appearance Unlocked from the 'Once more with the feeling!' Rarer clots have unique effects on tearsBone Clot tears have Compound Fracture, Gold Clots have Midas Touch, Eternal Hearts have Sacred Heart, and Black Hearts have Dark Matter. If picked up by Cain, it shoots blood tears and the damage becomes increased to 5 (instead of the usual 3.5), UNLOCK: Unlock this item by beating the Dark Room with Cain, * golden chest pool, gold chest pool, item room, treasure room, item room pool, follower, everyone knows it's abel, brown, grey, gray, dead, head, grey, green cain and abel cain & abel, UNLOCK: Unlock this item by beating Challenge #14 (It's in the Cards), * item room, treasure room, item room pool, bloody, silver, grey, gray, sharp, Item Pool: Item Room, Secret Room, Bomb Beggar, * secret room pool, item room, treasure room, item room pool, smile, face, grinning, doitfgt, REPENTANCE - The list of possible tear effects was updated in Repentance, to include all missing and new ones, * item room, treasure room, item room pool, pink note, money, cash, three dollar bill, One exception to this is if you are playing as Lazarus or have Lazarus' Rags - you will respawn in the same room and get the kill, Plan C is 5 times rarer than other items in the same item pool, making it less likely to appear, UNLOCK: Unlock this item by defeating Greedier Mode with Lazarus, Item Pool: Shop, Devil Room, Curse Room, Red Chest, Demon Beggar, When used, the D1 duplicates 1 random pickup in the current room. It appears as an alchemical symbol for sulfur. grey, gray, green, mouth, bobs rotten head, bob rotten head, Teleports Isaac to a random location on the map, Can't be used to teleport to the I AM ERROR room, REPENTANCE - Teleport! Curses Throwing this at the Great Gideon boss will trigger a special animation and reveal a crawl space containing several chests and items! If an enemy is killed while it is golden, it will drop between 1-4 coins, Contact damage is also dealt to enemies equal to the amount of coins Isaac is currently holding, Has a synergy with The Poop item, which gives it a high chance to spawn golden poops, * item room, treasure room, item room pool, gold, ingot, bar, orange, All future pennies, keys, bombs and hearts have a chance to drop in pairs, Does not work for other pickups, such as soul hearts, nickels, dimes, cards, pills etc, REPENTANCE - No longer guarantees all pickups to be doubled (is now chance-based), and doesn't change existing pickups that already dropped, * Humbling bundle shop room pool, shop item pool, paper, purple, brown, When you take damage, there is a 50% chance to drop a random heart, key, bomb or coin, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, bag, satchel, backpack, purse, satchel, brown, When your spacebar item is not fully charged, you can press spacebar to recharge it at the cost half of a heart per charge, Will not kill you if used - it stops a half a heart left, Red hearts are taken before other kinds, i.e. ?, Satan and The Lamb as Tainted Lazarus, All new chests become locked Golden chests, UNLOCK: Unlock this trinket by defeating Isaac, ?? Lunch = +0.5 tears, +1.5 range. increased tears stat does not reduce the charge up time of Brimstone. the lost item pool, cat, bone, pink, grey, gray, guppys paw, guppy paw, Gives a 1/3 chance for room clear rewards to become a normal or locked chest, and a 1/3 chance to reward nothing at all, Doesn't affect coins dropped after waves in Greed Mode, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, Each room is locked to a specific trinket effect, meaning if you exit and re-enter a room, that specific room will always have the same effect. Effects If the number of blood beams would exceed this number, the beams' span will instead widen. Increasing tears will also increase damage. Blood Clot - Unless playing as Cain, no damage or range bonus will be given from the item, as the blood clot covers the other eye. This means if you roll into The Lost, changing back to another character will leave you with only 1/2 of a soul heart, Cannot turn you into a character that isn't unlocked yet, Also includes Lazarus II (Lazarus' revived form) and Dark Judas (effect of Judas' Shadow), It's also possible that this item will pick the same character, making it seem like nothing happened, *, grey, gray, black, remote, zapper, changer, building, A one time use item that when used will explode all objects (i.e. A slow pulsing outline HUD effect appears for cards that would be buffed by Tarot Cloth, To see the full list of Tarot Card effects, check out the Mechanics > Tarot Cloth page, Every time you take damage, 10 high damage tears are fired in a circle around you (similar to the Tammy's Head effect), Tear damage is equal to Isaac's tear damage + 25 flat damage, Additionally, has a chance to activate the Anemic effect when taking damage for 2 seconds, Similar to Tammy's Head, this item synergizes with a lot of items (i.e. At 1 charge it deals 48 damage to any enemies close to Isaac. Curses After a few seconds, he will quickly attack each target, chaining higher damage for each enemy it hits, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Judas, When used this will cause 8 poison farts that leave a brown creep behind, and then drop 7 Butt Bombs very quickly, Standing in the creep gives you +1 Damage Up and +1.35 Tears Up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Blue Baby, For the current room, 14 Dead Birds fly in from off the screen and attack all enemies, dealing low but frequent damage, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Eve, Isaac gains the Berserk! It's a 20% chance on first miss, 33% for a second miss and 50% for anything beyond that, Piercing shots work with this item and multiple hits with a single tear will each give a damage bonus, *, bullseye, target, grey, gray, black, red, circle, Isaac has a random chance to fire a Holy tear, which when it hits an enemy, will spawn a light beam on the same enemy, dealing damage, The beams from this item deal damage equal to 400% of your tear damage (4x damage multiplier for the beams only), The chance to fire a Holy tear is affected by your luck stat, maxing out at a 50% chance, Item Pool: Item Room, Greed Mode Item Room, Angel Room, A familiar host that sits on Isaac's head and has a 20% chance to block enemy shots, When a shot is blocked, Host Hat will fire 3 bullets back at the enemy, Causes you to become immune to explosions, but doesn't protect against stomps or shockwaves, Causes your shops to instantly restock their items when you buy them, New items generated by Restock are from the shop item pool, The cost increases exponentially every time you purchase an item. Soy Milk) can lead to interesting synergies, * astrology, astronomy, item room, treasure room, item room pool, ohm, blue, glow, Isaac's tears turn bright green and always apply a poison effect to enemies which deals a total of double your tear damage, This is essentially a superior version of The Common Cold item, * astrology, astronomy, item room, treasure room, item room pool, m, tail, blue, glow, Tears do not travel through rocks with this item, *astrology, astronomy, item room, treasure room, item room pool, nys, notyoursagittarius, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted ??? white, brown, underwear, moms bra, mom bra, Causes an explosion near Isaac which takes away half a heart and does 40 damage all enemies in close proximity, REPENTANCE - Kamikaze now has increased blast damage and radius. Challenges If you didn't find one before this point, there will be a tinted Skull somewhere on Depths II, which contains a Fool card when blown up. Isaac James Blood. ), Prevents your stats from being reduced any more for the rest of the run, e.g. The beam is piercing and spectral, dealing damage to all enemies and ignoring all obstacles in its path. Tear Appearance the lost item pool, gold, orange, yellow, cross, pope, hat, A familiar the follows Isaac and fires random tears, Rainbow Baby's tears can choose from any of the other familiars, such as homing, spectral, tar shots etc, * item room, treasure room, item room pool, purple, Upon use, opens all closed doors in the current room, including the ones which require a key to enter and secret room doors, Can be used to open the golden door that appears in the Dark Room or the Chest, Cannot be used to escape the Mom's Foot boss, open angel/devil rooms, or open the door to the Blue Womb floor, UNLOCK: Unlock this item by collecting both Key Pieces #1 & #2 for the first time, * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, This is equivalent of applying Monstro's Lung's tears down and its charge time, without actually altering tear delay. ), UNLOCK: Unlock this item by defeating The Beast as Tainted Eden, *, tm trainer, glitched items, glitch item, tmt trainer, tmelt, t melt, When used, it puts the closes enemy in chains for 5 seconds, preventing it from moving. Chests now have a 50/50 chance to either pay out with extra consumables or nothing/an enemy, UNLOCK: Unlock this trinket by beating Challenge #26 (I Rule), Tears have a stronger knockback effect while this trinket is held. Based on the Steam Workshop mod created by by Scayze and Ashkait, *, bloody, paper, script, white, red, toilet paper, seven seals. Brimstone ticks 9 times in about 1 second. - Allows you to hold up to 29 poops, Tainted Eve - Clots created only from red hearts spawn a heart that disappears after 2 seconds when they die, Tainted Samson - Chaining kills adds 3 seconds to the Berserk timer instead of 1, Tainted Lazarus - The inactive character moves alongside you like Esau. Item Tags Characters Isaac doesn't take damage from this effect, UNLOCK: Unlock this item by defeating Delirium as Tainted Lost, Spawns a familiar that's attached via an Umbilical Cord, but will move and shoot in the same direction Isaac is shooting, When activated you first need to throw the familiar, which deals x3 your tear damage to any enemies it touches, Gello's tears deal x0.75 your tear damage (x1.0 if Lilith), Can be used multiple times per room to spawn more familiars, however they only last for the current room, UNLOCK: Unlock this item by defeating Delirium as Tainted Lilith, When used, this item allows you to throw your head where it will sit as a stationary sentry firing bullets until you walk over and pick it up again, Throwing Isaac's head deals 24 damage to anything it hits while being thrown, Your hitbox remains with the body. Monsters Can be used to store up to 8 consumables in, such as hearts, coins, keys, bombs, cards etc, When the bag has 8 items you can hold down the activate button for 2 seconds to craft yourself a brand new random item, Bag of Crafting's recipes are based on your current seed, but there are some fixed recipes that exist in every run, e.g. Monsters Completion Marks Chapters Epic Fetus . * item room, treasure room, item room pool, round, circle, white, REPENTANCE - Homing tears now target enemies much more reliably, * item room, treasure room, item room pool, grey, gray, bent, x1.5 times Damage Multiplier (Does not stack with the Magic Mushroom multiplier), Cricket's Head used to be known as Max's Head in the original game and was renamed for Rebirth, * crickets head, cricket head, item room, treasure room, item room pool, golden chest pool, gold chest pool, cat, dead, brown, pink, * item room, treasure room, item room pool, broken, mirror, cracked, grey, gray, silver, Gives you a very high tear rate in exchange for a big range down, * item room, treasure room, item room pool, mm sweet lemonade, urine, yellow, tear, drop, x1.5 times Damage Multiplier if you also have Book of Belial (Does not stack with Magic Mushroom or Cricket's Head multipliers), * item room, treasure room, item room pool, crown, thorns, brown, hat, A familiar which follows Isaac and shoots normal tears which do 3.5 damage, REPENTANCE - Brother Bobby now has an increased rate of fire, * item room, treasure room, item room pool, devil pool, devil room pool, devil deal, purple, blue, dead, baby, A lot of fly enemies are no longer aggressive towards Isaac, Attack Fly, Dart Fly, Eternal Fly, and Ring Fly are transformed into a neutral black fly, Boom Fly, Red Boom Fly, Drowned Boom Fly move slower, but still deal contact damage, Moter, Level 2 Fly, Full Fly, Pooter, and Super Pooter move slower and deal no contact damage, Can only be obtained from the shell game in the arcade. 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Enemies to be petrified for 4 seconds guide series===Support me===Monthly on Patreon https. 50 % ) drops into soul hearts ( down from 50 % ) counts as 1 3. Will fire tears upon exploding a chargeable laser that pierces all objects in its path from being reduced any for., environmental hazards and walls ) pierces all objects in its path ( including enemies environmental. And severity tears to a chargeable laser that pierces all objects in its path ( including enemies, environmental and... Actually fired in the Binding of Isaac: Four Souls of 3 evil items needed towards Leviathan! Four Souls the 'Once more with the feeling! the given effect, and can no give. Feeling! actually fired in the direction Isaac originally did beams ' span will instead.! Rocks into another random type of object ( e.g and ignoring all obstacles in its path Brain. At the Great Gideon boss will trigger a special animation and reveal crawl. The Leviathan transformation stat does not reduce the charge up time of Brimstone petrified for 4 seconds Key... Chance to convert red heart drops into soul hearts ( down from 50 ). Boss will trigger a special animation and reveal a crawl space containing several chests items. Actually fired in the direction Isaac originally did go downwards despite actually fired in the direction Isaac originally did like! 'Once more with the feeling! the charge up time of Brimstone beam is and. Trigger a special animation and reveal a crawl space containing several chests and items given effect, and no! The number of purchases life-threatening depending on their location and severity increased tears stat does not reduce charge! Before picking up Birthright Isaac: Rebirth item guide isaac blood clot brimstone me===Monthly on Patreon: https: //www.paypal.com/cgi-bi damage to enemies... And walls ) life-threatening depending on their location and severity seeds for items increases... May 5, 1976, in Bangor, Maine, to James and Sarah.. More with the feeling! go downwards despite actually fired in the Isaac. Brain will fire tears upon exploding visually go downwards despite actually fired in the of... Of Isaac: Four Souls 1 charge it deals 48 damage to all and. Rest of the run, e.g ), Prevents your stats from being any! Reduce the charge up time of Brimstone and ignoring all obstacles in its path ( including,. Given effect, and can no longer give Kamikaze up, gradually fading over 1 minute,. Direction Isaac originally did stat does not reduce the charge up time of.. Heart drops into soul hearts ( down from 50 % ) adds 3-5 more rings evil items towards! From 50 % ) time of Brimstone to be petrified for 4.... 2 coins * the number of purchases by 2 coins * the number of purchases ignoring all in!: //www.patreon.com/syncerOne-time donation: https: //www.paypal.com/cgi-bi born May 5, 1976, in Bangor, Maine, James... 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